Nuclear Magnetic Resonance (NMR) Spectroscopy Services

A Nuclear Magnetic Resonance Spectroscopy (NMR) system applies a strong static magnetic field along with a weakly oscillating field. The resultant NMR signals result from the specific magnetic properties of certain atomic nuclei. Nuclear magnetic resonance spectroscopy is widely used to determine the structure of organic molecules in solution and study molecular physics, crystals as well as non-crystalline materials.

We have the capability and equipment to do 1D, 2D and 3D NMR as well as Solid-State NMR.

To enhance our solid state NMR capability, we are acquiring a Phoenix 1.6 mm HXY solid-state NMR probe, which will allow triple resonance experiments up to 40 kHz MAS.


Our equipment can accommodate a wide range of temperatures, including cryogenic reaction conditions, for liquid and solid samples: including fluid, powdered, bulk material, and crystalline samples. All techniques are non-destructive, preserving your samples for further analysis. Our spectroscopy services cover the complete range of possibilities from raw data only to complete structure analysis and interpretation.


  • Quantitative measurement of content & purity of desired compounds
  • Precise determination of the chemical structure of organic or inorganic compounds
  • Identification of chemical unknowns or contaminants
  • Qualitative characterization of the primary and secondary structures of enzymes
  • Reaction chemistry analyses: kinematics, conformational rearrangements, phase changes, molecular solubility, and diffusion behavior of solutes.


  • What it is great for:
    • Quick & easy sample preparation
    • Broad range of applications
    • Non-invasive and non-destructive
    • Can be Quantitative
    • Optimized for nonselective analyses (due to simultaneous molecular detection within a sample)
    • Superb reproducibility for multiple trials
  • Limitations:
    • Less sensitive than Mass Spectrometry and some other chemical analytics techniques.
    • Limited to NMR-active nuclei


Bruker Avance III-HD 600 MHz NMR Spectrometer
The powerhouse in our NMR toolkit, this system combines a 14.1 Tesla magnet with a state-of-the-art multinuclear Prodigy CryoProbe to achieve high sensitivity detection of most NMR-active nuclei. Variable temperature experiments between -40 C and + 80 C can be performed for solution-state samples.

For lower-frequency nuclei (as low as 109Ag) or 1H/19F decoupling and correlation experiments, we are equipped with a multinuclear Bruker SmartProbe, with a variable temperature range of -150 C to +150 C. The SmartProbe contains quartz glassware to minimize 11B background signal.

This spectrometer is also capable of broadband solid-state NMR with high-power decoupling up to 15 kHz MAS.


Bruker Avance III-HD 500 MHz NMR Spectrometer

For 500 MHz field-specific samples, we also possess an 11 Tesla instrument equipped with the Prodigy CryoProbe.  For lower-frequency nuclei, 1H/19F correlation or decoupling experiments, we have a Bruker SmartProbe. 


Varian Inova-500 NMR Spectrometer

The Varian Inova-500 features 3 radiofrequency channels with waveform generators.  It is best used for triple HCN experiments on a 5 mm Nalorac IDTG triple-resonance probe or dual-channel broadband experiments over a wide temperature range from -100 C  to +150 C.


300 MHz

For field-specific applications, we also possess a 300 MHz spectrometer.